ThinPrep® PreservCyt Collection Vials

The cervical sample collection and preservation that is tested and trusted by healthcare professionals all over the world.

Gloved hand holding vial




    A Wealth of Knowledge in a Single Vial

    The ThinPrep® Pap Test collection vial is a worldwide standard for cervical sample collection and preservation, trusted by healthcare professionals around the world. More than 1 billion ThinPrep vials have been used globally for cervical cancer screening. Only a single sample is required for both cytology and molecular testing.1

    In addition to the Aptima® HPV assay, Aptima® Combo 2 and Aptima® Trichomonas vaginalis Assays can also be tested from the vial.

    Trust the Track Record

    The ThinPrep Pap Test collection vial enables an optimal preservation of cellular material, mRNA and DNA.


    Significantly more effective than conventional Pap smear for the detection of Low-grade Squamous Intraepithelial Lesion (LSIL) and more severe lesions (HSIL).2


    Improved ability to detect glandular disease compared to conventional Pap.2


    Approved for use with all leading FDA-approved and CE-marked HPV tests*

    Graphic showing connection between Hologic products

    Working With You to Advance Cervical Health

    We pride ourselves on being champions of women’s health and global leaders in screening, dedicated to advancing the accuracy and early detection of cervical cancer. From HPV to cytology, and now also AI-based digital diagnostics, we offer a comprehensive and unique screening portfolio, from sample collection to diagnosis.

    Advancing the Early Detection of Cervical Cancer

    250+ Publications

    peer reviewed studies confirming ThinPrep performance3

    1+ Billion

    ThinPrep Pap tests have been performed4

    59.7% Higher HSIL

    detection than conventional pap testing2

    Collection vial in white background

    The ThinPrep Pap Test Product Design

    Trusted performance across all grades of cervical disease:

    • Safety seal, torque mark and fill level mark
    • Collection device rinsed in ThinPrep Vial.2
    • Significantly more epithelial cells collected compared to conventional pap.5
    • Immediate fixation maintains cell quality.5
    • 6 weeks storage at room temperature for cytology.2
    • Methanol base (no formaldehyde) protects molecular content for analysis.6
    • 4mL pre-aliquot removal volume facilitates multiple ancillary tests.2

    ThinPrep Specimen Collection with Non-Gyn Application

    These solutions have a wider application beyond cervical health,and come with a standardised workflow. Browse options for collection and cytology preparation, including fine needle aspirates, urine, effusions, respiratory and gastrointestinal tract sample types.

    Image Gallery9

    Case Study: A World First Trial

    Lab CEO Dr Dietmar Klimas and cytologist Heike Lesle-Amour share their experiences of trialling the Genius™ Digital Diagnostics System in one of Europe's largest labs.

    A Patient Friendly Experience

    Out-of-the-vial testing minimises the number of samples required for multiple test results. For cervical cancer screening in the case of a first positive or abnormal result, the reflex testing can be directly performed from the same primary sample. This versatile application improves patient comfort and avoids additional follow-up.

    Female patient sitting on hospital examination table talking to healthcare professional

    Evidence. Insight. Collaboration.

    Our education portal improves patient care through excellence in education, communication of clinical and scientific evidence, and partnerships with the healthcare community.

      * Aptima HPV assay, Aptima HPV 16 18/45 Genotype assay, Cervista HPV HR test, Cervista HPV 16/18 test, Roche cobas HPV test and Hybrid Capture 2 HPV DNA test
      1. ThinPrep® Pap Test PreservCyt Solution, Instructions for Use AW-22719-001 Rev 001
      2. ThinPrep 5000 Processor User Manual, MAN-07493-002 Rev 003
      3. View Published Data
      4. Data based on Hologic sales numbers since launch in 2012 to 31Jan2020. File reference: AHPVtotalnumberJan2020 (Page 6
      5. Hutchinson ML, Isenstein LM, Goodman A, Hurley AA, Douglass KL, Mui KK, et al. Homogeneous Sampling Accounts for the Increased Diagnostic Accuracy Using the ThinPrepTM Processor. Am J Clin Pathol. 1994;101:215-9.
      6. Powell N, Smith K, Fiander A. Recovery of human papillomavirus nucleic acids from liquid-based cytology media. J Virol Methods. 2006 137:58-62.
      7. ThinPrep ThinPrep® PreservCyt® Solution, Instructions for Use AW-22939-001 Rev 001
      8. ThinPrep UroCyte PreservCyt, Instructions for Use AW-22938-001 Rev 001
      9. Images received from Cytopathology Department, Llandough Hospital, Wales

      Safety Data Sheets

      Package Inserts


      Hologic BV, Da Vincilaan 5, 1930 Zaventem, Belgium.

      Notified Body number wherever applicable
      EC Representative Information wherever applicable