Sonata® Fibroid Ablation System
Treat symptomatic uterine fibroids with intrauterine ultrasound combined with radiofrequency ablation.
An Incisionless Fibroid Solution
Offer your patients an incisionless, uterine-sparing fibroid treatment with the Sonata System. The real-time intrauterine ultrasound and proprietary SMART OS™ technology enables precise targeting of submucosal, intramural and most subserosal fibroids.1
Access without Incisions
Ablate a wide range of fibroids in a single, incisionless, transcervical procedure.
Visualise in Real-Time
Locate fibroids with an intrauterine ultrasound probe.
Treat with Precision
Target and treat fibroids with controlled ablations using SMART OS technology.
Improving Patient Care is Within Your Control
For many women, the diagnosis and treatment of uterine disorders is a long, painful and frustrating journey. Our team pioneers gynaecological, diagnostic and surgical solutions that give professionals greater confidence in patient diagnosis and more choice over treatment options.
Sonata Fibroid Ablation System is part of the Hologic Uterine Health Portfolio.
Clinical Evidence
Results of the SONATA study:
86%
reported lighter periods within 3 months2
96%
reported improved symptoms within 12 months3
97%
were satisfied and would recommend Sonata to a friend3
99%
did not require surgical reintervention within 12 months3
Targeted Fibroid Treatment
The Sonata treatment device combines a high-resolution intrauterine ultrasound probe for imaging with a handpiece for scalable volumetric radiofrequency ablation for targeted treatment of symptomatic fibroids.
1. See: Fibroids are located from inside the uterus.
2. Target: Ablation is planned using the SMART Guide, a graphical real-time overlay on the ultrasound image. This includes several safety features and does not require any manual measurements.
3. Treat: Needle electrodes are inserted into the indicated location of the fibroid and RF-energy is delivered for volumetric ablation.
The Sonata System1
The Sonata treatment device consists of a reusable ultrasound probe connected to a single-use handpiece that delivers radiofrequency (RF) energy to ablate fibroids transcervically. Additional components include a cart, RF generator, a SMART tablet, SMART OS guidance software and accessories.
Sonata Treatment Device
The radiofrequency ablation handpiece connects to the intrauterine ultrasound probe. Once combined, the treatment device can locate fibroids from within the uterus and deliver RF energy to fibroids.
Capital Equipment
The RF generator provides radiofrequency energy and regulates real-time control of ablation. The SMART tablet enables ultrasound imaging and graphical ablation planning. The cart houses the tablet, generator, power components and a storage tray.
Software
The SMART OS guidance software installed on the SMART tablet streamlines ablation planning and communication between the generator and the handpiece.
Accessories
The three-meter detachable and reusable RFA handpiece cable connects the handpiece to the generator, which enables power to the handpiece.
The single-use dispersive electrodes return RF energy from the handpiece back to the generator via two flexible pads, one placed on each thigh.
Setting Margins of Ablation in Real Time
The SMART OS guide technology overlays graphical indicators on the ultrasound image to help target fibroids and accurately position the introducer and needle electrodes, while the ablation zone and thermal safety border help protect adjacent tissue.1
Patient's journey with the Sonata Fibroid Treatment
Learn about Emma’s journey, from the burden of her symptoms to getting diagnosed with fibroids and finally receiving the Sonata Treatment, which has drastically improved her quality of life.
Evidence. Insight. Collaboration.
Our education portal improves patient care through excellence in education, communication of clinical and scientific evidence, and partnerships with the healthcare community.
Insights
Sonata Intrauterine Ultrasound (IUUS) Probe Instructions for Use. LS06534.D. SONATA2-110/-220 with Radiofrequency Handpiece RFA-002, RFA Handpiece Cable ACCY-008, and Software SW-002 Instructions for Use. LS 03818-013 REF-009. https://www.hologic.com/package-inserts/gyn-surgical-products/ sonata-transcervical-radiofrequency-ablation Last accessed: 05.2026.
Shifrin G, Engelhardt M, Gee P, Pschadka G. Transcervical fibroid ablation with the Sonata system for treatment of submucous and large uterine fibroids. Int J Gynaecol Obstet. 2021;1-7.
Chudnoff S, Guido R, Roy K et al. Ultrasound-Guided Transcervical Ablation of Uterine Leiomyomas. Obstet Gynecol. 2019; 133:13-22.
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