Panther Fusion® Paraflu Assay

A fully-automated approach to respiratory testing of parainfluenza 1, 2, 3 and 4 in one single assay.1

Assay box on lab background




    Panther Fusion Paraflu Assay

    The Panther Fusion Paraflu assay is a multiplex real-time PCR (RT-PCR) in vitro diagnostic test for the rapid and qualitative detection and differentiation of parainfluenza 1 virus (HPIV-1), parainfluenza 2 virus (HPIV-2), parainfluenza 3 virus (HPIV-3) and parainfluenza 4 virus (HPIV-4). Diagnose samples from nasopharyngeal (NP) swab specimens obtained from individuals exhibiting signs and symptoms of a respiratory tract infection.1

    Increase Efficiency & Reduce Costs

    Personalise your patient testing by running Panther Fusion Paraflu assay alone or in conjunction with other Panther Fusion respiratory assays.1

    Protecting Children

    HPIVs commonly infect infants and young children. HPIV-1 and HPIV-2 both cause croup, with HPIV-1 most often identified as the cause in children. Both can also cause upper and lower respiratory illness and cold-like symptoms.1,2

    Differentiate Results

    Four targets in one assay, including HPIV-3, associated with bronchiolitis, bronchitis, and pneumonia, and HPIV-4 which may cause mild to severe respiratory tract illnesses.1

    Testing Variety

    The assay can be run alongside current infectious disease, women’s health and virology assays, enabling laboratories to unlock the free capacity on their existing Panther Systems.

    Technician walking through Panther systems in a lab setting

    Simplify & Scale the Future of Diagnostics

    The Panther Fusion Paraflu Assay is part of the Hologic Molecular Scalable Solution, a portfolio combining a broad, high-performing assay menu with high-throughput automation. Designed to flexibly scale to meet your needs, from a single patient result to population-level screening.

    Be Prepared for the Winter Respiratory Season

    The Panther Fusion assay shows excellent clinical performance.1

    100% Sensitivity

    100% specificity Parainfluenza 1

    100% Sensitivity

    100% specificity Parainfluenza 2

    100% Sensitivity

    99.6% specificity Parainfluenza 3

    98.1% Sensitivity

    100% specificity Parainfluenza 4

    Right Patient. Right Test. Right Time.3

    • From true on-demand testing to high-throughput
    • No sample batch constraints, prioritise urgent samples
    • First results in 2.4 hours
    • Run multiple assays from a single specimen tube at the same time
    • Single dose, ready-to-use-assay reagent cartridge
    • Long onboard stability of fluids and reagents
    Lab technician carrying a tray of specimens to insert into Panther system
    Lab technician pressing buttons on monitor

    Verified Sample Collection

    The Panther Fusion Paraflu assay is validated for nasopharyngeal swabs in viral transport medium and universal transport medium.1

    Evidence. Insight. Collaboration.

    Our education portal improves patient care through excellence in education, communication of clinical and scientific evidence, and partnerships with the healthcare community.

      1. Panther Fusion Paraflu assay [package insert]. AW-23708-001 Rev 001. San Diego, CA: Hologic, Inc.; 2022.
      2. Oh DY, Biere B, Grenz M, Wolff T, Schweiger B, Dürrwald R, Reiche J. Virological Surveillance and Molecular Characterization of Human Parainfluenzavirus Infection in Children with Acute Respiratory Illness: Germany, 2015-2019. Microorganisms. 2021 Jul 14;9(7):1508. doi: 10.3390/microorganisms9071508. PMID: 34361941; PMCID: PMC8307145
      3. Panther/Panther Fusion System Operator´s Manual. AW-26055-001 Rev 001, San Diego, CA: Hologic Inc.; 2022.


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